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Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite.

Publication ,  Journal Article
Schroeck, FR; Donatucci, CF; Smathers, EC; Sun, L; Albala, DM; Polascik, TJ; Moul, JW; Krupski, TL
Published in: Cancer
November 15, 2008

BACKGROUND: Both the 5-item short version of the International Index of Erectile Function (IIEF-5) and the Expanded Prostate Cancer Index Composite (EPIC) have been used to assess erectile function. In this study, the authors compared various definitions of potency according to the IIEF-5 and the EPIC. METHODS: Patients with prostate cancer who had completed the IIEF-5 and the EPIC within 7 days of each other were included. The Spearman correlation coefficient (rho) was calculated to assess the relation between IIEF-5 and EPIC sexual domain scores. Concordance of potency rates by IIEF-5 and EPIC was assessed in cross-tabulations. By calculating the area under the receiver operator characteristics (ROC) curve (AUC), the authors ascertained the discriminative ability of the IIEF-5 score to identify potent men as defined by the EPIC. RESULTS: Analyzing 102 questionnaire pairs, IIEF-5 and EPIC domain scores were found to be highly correlated (rho = 0.776). EPIC sexual domain scores > or =60 had high concordance with IIEF-5 scores > or =17 (98%) and with nearly all single-item definitions of potency (> or =71%). However, an EPIC sexual domain score > or =80 was a very strict definition of potency, and only 54% of patients with IIEF-5 scores > or =22 met this threshold. On the basis of ROC analysis (AUC = 0.90), an IIEF-5 score > or =20 was identified as the ideal cutoff for defining potency and corresponded with an EPIC sexual domain score > or =60. CONCLUSIONS: IIEF-5 and EPIC scores were highly correlated, but potency rates varied widely, depending on the definition of potency. The current results help with the interpretation of sexual function outcomes data in patients with prostate cancer.

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Published In

Cancer

DOI

ISSN

0008-543X

Publication Date

November 15, 2008

Volume

113

Issue

10

Start / End Page

2687 / 2694

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • ROC Curve
  • Quality of Life
  • Prostatic Neoplasms
  • Penile Erection
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Humans
 

Citation

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Schroeck, F. R., Donatucci, C. F., Smathers, E. C., Sun, L., Albala, D. M., Polascik, T. J., … Krupski, T. L. (2008). Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite. Cancer, 113(10), 2687–2694. https://doi.org/10.1002/cncr.23887
Schroeck, Florian R., Craig F. Donatucci, Emily C. Smathers, Leon Sun, David M. Albala, Thomas J. Polascik, Judd W. Moul, and Tracey L. Krupski. “Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite.Cancer 113, no. 10 (November 15, 2008): 2687–94. https://doi.org/10.1002/cncr.23887.
Schroeck FR, Donatucci CF, Smathers EC, Sun L, Albala DM, Polascik TJ, et al. Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite. Cancer. 2008 Nov 15;113(10):2687–94.
Schroeck, Florian R., et al. “Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite.Cancer, vol. 113, no. 10, Nov. 2008, pp. 2687–94. Pubmed, doi:10.1002/cncr.23887.
Schroeck FR, Donatucci CF, Smathers EC, Sun L, Albala DM, Polascik TJ, Moul JW, Krupski TL. Defining potency: a comparison of the International Index of Erectile Function short version and the Expanded Prostate Cancer Index Composite. Cancer. 2008 Nov 15;113(10):2687–2694.
Journal cover image

Published In

Cancer

DOI

ISSN

0008-543X

Publication Date

November 15, 2008

Volume

113

Issue

10

Start / End Page

2687 / 2694

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Severity of Illness Index
  • ROC Curve
  • Quality of Life
  • Prostatic Neoplasms
  • Penile Erection
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Humans