New light on an age-old issue.
Publication
, Journal Article
Whitson, HE; Pieper, CF; Cohen, HJ
Published in: Mech Ageing Dev
November 2008
In this issue, Varadhan and colleagues propose a methodologic framework that seeks to quantify impaired resiliency in dynamic systems underlying the frailty syndrome. We view this work, which is based on modeling stimulus-response data, as an exciting expansion of longstanding theories of age-related decline in physiologic reserve across systems. We outline ways in which this methodology might make substantial contributions in frailty research and clinical practice, and we discuss potential obstacles in its operationalization.
Duke Scholars
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Published In
Mech Ageing Dev
DOI
ISSN
0047-6374
Publication Date
November 2008
Volume
129
Issue
11
Start / End Page
673 / 674
Location
Ireland
Related Subject Headings
- Time Factors
- Systems Biology
- Stress, Physiological
- Reproducibility of Results
- Phenotype
- Models, Biological
- Humans
- Homeostasis
- Gerontology
- Frail Elderly
Citation
APA
Chicago
ICMJE
MLA
NLM
Whitson, H. E., Pieper, C. F., & Cohen, H. J. (2008). New light on an age-old issue. Mech Ageing Dev, 129(11), 673–674. https://doi.org/10.1016/j.mad.2008.09.006
Whitson, Heather E., Carl F. Pieper, and Harvey J. Cohen. “New light on an age-old issue.” Mech Ageing Dev 129, no. 11 (November 2008): 673–74. https://doi.org/10.1016/j.mad.2008.09.006.
Whitson HE, Pieper CF, Cohen HJ. New light on an age-old issue. Mech Ageing Dev. 2008 Nov;129(11):673–4.
Whitson, Heather E., et al. “New light on an age-old issue.” Mech Ageing Dev, vol. 129, no. 11, Nov. 2008, pp. 673–74. Pubmed, doi:10.1016/j.mad.2008.09.006.
Whitson HE, Pieper CF, Cohen HJ. New light on an age-old issue. Mech Ageing Dev. 2008 Nov;129(11):673–674.
Published In
Mech Ageing Dev
DOI
ISSN
0047-6374
Publication Date
November 2008
Volume
129
Issue
11
Start / End Page
673 / 674
Location
Ireland
Related Subject Headings
- Time Factors
- Systems Biology
- Stress, Physiological
- Reproducibility of Results
- Phenotype
- Models, Biological
- Humans
- Homeostasis
- Gerontology
- Frail Elderly