A kiss of death--proteasome-mediated membrane fusion and programmed cell death in plant defense against bacterial infection.

Journal Article (Journal Article)

Eukaryotes have evolved various means for controlled and organized cellular destruction, known as programmed cell death (PCD). In plants, PCD is a crucial regulatory mechanism in multiple physiological processes, including terminal differentiation, senescence, and disease resistance. In this issue of Genes & Development, Hatsugai and colleagues (pp. 2496-2506) demonstrate a novel plant defense strategy to trigger bacteria-induced PCD, involving proteasome-dependent tonoplast and plasma membrane fusion followed by discharge of vacuolar antimicrobial and death-inducing contents into the apoplast.

Full Text

Duke Authors

Cited Authors

  • Pajerowska-Mukhtar, K; Dong, X

Published Date

  • November 2009

Published In

Volume / Issue

  • 23 / 21

Start / End Page

  • 2449 - 2454

PubMed ID

  • 19884251

Pubmed Central ID

  • PMC2779745

Electronic International Standard Serial Number (EISSN)

  • 1549-5477

International Standard Serial Number (ISSN)

  • 0890-9369

Digital Object Identifier (DOI)

  • 10.1101/gad.1861609


  • eng