Maternal and childhood nutrition and later blood pressure levels in young Guatemalan adults.

Journal Article (Journal Article)

BACKGROUND: Low birth weight and subsequent rapid child growth are associated with later blood pressure levels. The role of maternal and child nutrition in this association remains unclear. METHODS: We studied 450 men and women (ages 21-29 years) born during a randomized trial of protein-energy supplementation (Atole) vs low energy/no protein supplementation (Fresco) in pregnancy and early childhood in four rural Guatemalan villages from 1969 to 1977. RESULTS: Protein-energy supplementation was not associated with differences in blood pressure in adulthood (diastolic blood pressure (DBP): beta = 0.69 mm Hg, 95% confidence internal (CI) (20.82-2.19); P = 0.37; systolic blood pressure (SBP): beta = 0.17 mm Hg, 95% CI (21.68-2.02); P = 0.86). Within the Atole group, maternal height was associated with later SBP (0.22 mm Hg/cm, 95% CI (20.002-0.45); P = 0.05). No other associations between maternal nutritional status, birth size, child growth, or supplement intake were observed for adult blood pressure. CONCLUSIONS: Our data do not support the role of maternal nutrition during pregnancy, birth size, or early child growth in programming adult blood pressure. Likewise, we found no effect of protein-energy supplementation in pregnancy or in early childhood on blood pressure in young adults.

Full Text

Duke Authors

Cited Authors

  • Webb, AL; Conlisk, AJ; Barnhart, HX; Martorell, R; Grajeda, R; Stein, AD

Published Date

  • August 2005

Published In

Volume / Issue

  • 34 / 4

Start / End Page

  • 898 - 904

PubMed ID

  • 15894592

International Standard Serial Number (ISSN)

  • 0300-5771

Digital Object Identifier (DOI)

  • 10.1093/ije/dyi097


  • eng

Conference Location

  • England