Prospective thermal dosimetry: the key to hyperthermia's future.
PURPOSE: This review summarizes recent results from two randomized trials testing the complete response rate and local control benefits for the addition of hyperthermia to external beam radiation. METHODS: In both series, there was a statistically significant benefit to adjuvant hyperthermia. RESULTS: The establishment of a standardized nomenclature for clinical hyperthermia prescription will help to facilitate the broader usage of hyperthermia. CONCLUSIONS: Carefully conducted phase III trials with rigorous quality assurance must employ prospective thermal dosimetry to validate the role of hyperthermia in multi-modality therapy.
Jones, E; Thrall, D; Dewhirst, MW; Vujaskovic, Z
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