Interstitial hyperthermia in combination with brachytherapy.

Journal Article (Clinical Trial;Journal Article)

Flexible coaxial cables were modified to serve as microwave antennas operating at a frequency of 915 MHz. These antennas were inserted into nylon afterloading tubes that had been implanted in tumors using conventional interstitial implantation techniques for iridium-192 seed brachytherapy. The tumor volume was heated to 42-45 degrees C within 15 minutes and heating was continued for a total of 1 hour per treatment. Immediately following a conventional brachytherapy dose and removal of the iridium seeds the tumors were heated again in a second treatment. This interstitial technique for delivering local hyperthermia should be compatible with most brachytherapy methods. The technique has proved so far to be practical and without complications. Temperature distributions obtained in tissue phantoms and a patient are described.

Full Text

Duke Authors

Cited Authors

  • Coughlin, CT; Douple, EB; Strohbehn, JW; Eaton, WL; Trembly, BS; Wong, TZ

Published Date

  • July 1, 1983

Published In

Volume / Issue

  • 148 / 1

Start / End Page

  • 285 - 288

PubMed ID

  • 6344136

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/radiology.148.1.6344136


  • eng

Conference Location

  • United States