Breast self-examination: defining a cohort still in need.

Journal Article (Clinical Trial;Journal Article)

BACKGROUND: The value of breast self-examination (BSE) to detect early breast cancer is controversial. METHODS: Within an institutional review board-approved prospective study, 147 high-risk women were enrolled from 2004 to 2007. Yearly clinical examination, BSE teaching, and mammography were performed simultaneously followed by interval breast magnetic resonance imaging (MRI). Women underwent additional BSE teaching at 6 months. Women reporting a mass on BSE underwent clinical evaluation. RESULTS: Fourteen breast cancers were detected in 12 women. BSE detected 6/14 breast cancers versus 6/14 detected by MRI and 2/14 by mammography. Of 24 masses detected by BSE, 6/24 were malignant. The sensitivity, specificity, and predictive value of BSE to detect breast cancer were 58.3%, 87.4%, and 29.2%, respectively. The sensitivity, specificity, and predictive value of a Breast Image Reporting and Data System (BI-RADS) score of >or=4 on MRI were 66.7%, 88.9%, and 34.8%, respectively. CONCLUSIONS: BSE detects new breast cancers in high-risk women undergoing screening mammogram, CBE, and yearly breast MRI.

Full Text

Duke Authors

Cited Authors

  • Wilke, LG; Broadwater, G; Rabiner, S; Owens, E; Yoon, S; Ghate, S; Scott, V; Walsh, R; Baker, J; Soo, MS; Ibarra-Drendall, C; Stouder, A; Robertson, S; Barron, A; Seewaldt, V

Published Date

  • October 2009

Published In

Volume / Issue

  • 198 / 4

Start / End Page

  • 575 - 579

PubMed ID

  • 19800471

Electronic International Standard Serial Number (EISSN)

  • 1879-1883

Digital Object Identifier (DOI)

  • 10.1016/j.amjsurg.2009.06.012


  • eng

Conference Location

  • United States