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Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection.

Publication ,  Journal Article
Todd, JL; Lakey, J; Howell, D; Reidy, M; Zaas, D
Published in: Am J Transplant
May 2007

The incidence of atypical mycobacterial infection among solid organ transplant recipients is increasing. While lung transplant recipients in particular are at greater risk of atypical mycobacterial infection than other solid organ transplant recipients, it is typically confined to the lung and disseminated infection remains quite rare. We describe a case of disseminated Mycobacterium avium-complex (MAC) in a lung transplant recipient presenting as granulomatous liver disease with signs of portal hypertension. After identification of the infection and institution of proper therapy, the patient had significant improvement in both clinical signs of portal hypertension and liver function tests. Current literature suggests a favorable prognosis in most cases of MAC infection in lung transplant recipients with appropriate treatment. This case highlights the need to maintain an elevated index of suspicion for atypical pathogens with unusual clinical presentations among the lung transplant population.

Duke Scholars

Published In

Am J Transplant

DOI

ISSN

1600-6135

Publication Date

May 2007

Volume

7

Issue

5

Start / End Page

1300 / 1303

Location

United States

Related Subject Headings

  • Surgery
  • Prognosis
  • Mycobacterium avium-intracellulare Infection
  • Mycobacterium avium Complex
  • Male
  • Lung Transplantation
  • Lung
  • Liver Diseases
  • Liver
  • Hypertension, Portal
 

Citation

APA
Chicago
ICMJE
MLA
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Todd, J. L., Lakey, J., Howell, D., Reidy, M., & Zaas, D. (2007). Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection. Am J Transplant, 7(5), 1300–1303. https://doi.org/10.1111/j.1600-6143.2007.01748.x
Todd, J. L., J. Lakey, D. Howell, M. Reidy, and D. Zaas. “Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection.Am J Transplant 7, no. 5 (May 2007): 1300–1303. https://doi.org/10.1111/j.1600-6143.2007.01748.x.
Todd, J. L., et al. “Portal hypertension and granulomatous liver disease in a lung transplant recipient due to disseminated atypical mycobacterial infection.Am J Transplant, vol. 7, no. 5, May 2007, pp. 1300–03. Pubmed, doi:10.1111/j.1600-6143.2007.01748.x.
Journal cover image

Published In

Am J Transplant

DOI

ISSN

1600-6135

Publication Date

May 2007

Volume

7

Issue

5

Start / End Page

1300 / 1303

Location

United States

Related Subject Headings

  • Surgery
  • Prognosis
  • Mycobacterium avium-intracellulare Infection
  • Mycobacterium avium Complex
  • Male
  • Lung Transplantation
  • Lung
  • Liver Diseases
  • Liver
  • Hypertension, Portal