Skip to main content

Magnetic resonance imaging of the pancreas with gadolinium-DTPA.

Publication ,  Journal Article
Chezmar, JL; Nelson, RC; Small, WC; Bernardino, ME
Published in: Gastrointest Radiol
1991

Gadolinium (Gd)-DTPA was evaluated as a contrast agent for magnetic resonance (MR) imaging of the pancreas at 1.5T. Twenty-five patients were imaged with identical gradient-echo (GE) (TR 47, TE 13, 80 degree pulse angle) and spin-echo (SE) (TR 300, TE 15) MR sequences prior to and following an intravenous bolus of 0.1 mmol/kg Gd-DTPA. Marked pancreatic enhancement was demonstrated on dynamic sequential breath-hold GE images obtained immediately following the Gd-DTPA bolus (116% mean enhancement over pre-Gd-DTPA images). Enhancement decreased but persisted on the SE images obtained approximately 5 and 15 min following the Gd-DTPA bolus (65 and 60% mean enhancement, respectively). Five of the patients had a pancreatic mass. In these five patients, the enhancement of pancreatic tissue resulted in improved conspicuity of the mass. These initial results suggest that pancreatic enhancement occurs following an intravenous bolus of Gd-DTPA and has the potential to improve MR visualization of pancreatic masses.

Duke Scholars

Published In

Gastrointest Radiol

DOI

ISSN

0364-2356

Publication Date

1991

Volume

16

Issue

2

Start / End Page

139 / 142

Location

United States

Related Subject Headings

  • Pentetic Acid
  • Pancreatic Pseudocyst
  • Pancreatic Neoplasms
  • Pancreatic Diseases
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chezmar, J. L., Nelson, R. C., Small, W. C., & Bernardino, M. E. (1991). Magnetic resonance imaging of the pancreas with gadolinium-DTPA. Gastrointest Radiol, 16(2), 139–142. https://doi.org/10.1007/BF01887329
Chezmar, J. L., R. C. Nelson, W. C. Small, and M. E. Bernardino. “Magnetic resonance imaging of the pancreas with gadolinium-DTPA.Gastrointest Radiol 16, no. 2 (1991): 139–42. https://doi.org/10.1007/BF01887329.
Chezmar JL, Nelson RC, Small WC, Bernardino ME. Magnetic resonance imaging of the pancreas with gadolinium-DTPA. Gastrointest Radiol. 1991;16(2):139–42.
Chezmar, J. L., et al. “Magnetic resonance imaging of the pancreas with gadolinium-DTPA.Gastrointest Radiol, vol. 16, no. 2, 1991, pp. 139–42. Pubmed, doi:10.1007/BF01887329.
Chezmar JL, Nelson RC, Small WC, Bernardino ME. Magnetic resonance imaging of the pancreas with gadolinium-DTPA. Gastrointest Radiol. 1991;16(2):139–142.

Published In

Gastrointest Radiol

DOI

ISSN

0364-2356

Publication Date

1991

Volume

16

Issue

2

Start / End Page

139 / 142

Location

United States

Related Subject Headings

  • Pentetic Acid
  • Pancreatic Pseudocyst
  • Pancreatic Neoplasms
  • Pancreatic Diseases
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans