In vivo guidance and assessment of liver radio-frequency ablation with acoustic radiation force elastography.

Journal Article (Clinical Trial;Journal Article)

The initial results from clinical trials investigating the utility of acoustic radiation force impulse (ARFI) imaging for use with radio-frequency ablation (RFA) procedures in the liver are presented. To date, data have been collected from 6 RFA procedures in 5 unique patients. Large displacement contrast was observed in ARFI images of both pre-ablation malignancies (mean 7.5 dB, range 5.7-11.9 dB) and post-ablation thermal lesions (mean 6.2 dB, range 5.1-7.5 dB). In general, ARFI images provided superior boundary definition of structures relative to the use of conventional sonography alone. Although further investigations are required, initial results are encouraging and demonstrate the clinical promise of the ARFI method for use in many stages of RFA procedures.

Full Text

Duke Authors

Cited Authors

  • Fahey, BJ; Nelson, RC; Hsu, SJ; Bradway, DP; Dumont, DM; Trahey, GE

Published Date

  • October 2008

Published In

Volume / Issue

  • 34 / 10

Start / End Page

  • 1590 - 1603

PubMed ID

  • 18471954

Pubmed Central ID

  • PMC2610689

Electronic International Standard Serial Number (EISSN)

  • 1879-291X

Digital Object Identifier (DOI)

  • 10.1016/j.ultrasmedbio.2008.03.006


  • eng

Conference Location

  • England