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Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis.

Publication ,  Journal Article
Henderson, JM; Campbell, JD; Olson, R; Nelson, RC
Published in: Gastrointest Radiol
1988

One hundred patients with cirrhosis underwent abdominal computed tomography (CT) using a delayed contrast technique to determine liver and spleen volume. These scans were reviewed to screen this "at risk" population for hepatocellular carcinoma (HCC). Fifteen of the 100 screened patients had focal abnormalities suspicious for HCC. On biopsy, only 1 patient was shown to have HCC. The other 14 patients had either fatty infiltration or focal regeneration. In the same time interval, a total of 10 patients had histologically proven HCC. All presented with symptoms and died within 4 months of diagnosis. The results show that focal hepatic lesions can be detected by CT but in this population the lesions may not be due to HCC. The incidence of HCC was approximately 1%, probably reflecting a truly low incidence in this population.

Duke Scholars

Published In

Gastrointest Radiol

DOI

ISSN

0364-2356

Publication Date

1988

Volume

13

Issue

2

Start / End Page

129 / 134

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Liver Neoplasms
  • Liver Cirrhosis, Alcoholic
  • Liver Cirrhosis
  • Liver
  • Humans
  • Carcinoma, Hepatocellular
  • Biopsy
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Henderson, J. M., Campbell, J. D., Olson, R., & Nelson, R. C. (1988). Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis. Gastrointest Radiol, 13(2), 129–134. https://doi.org/10.1007/BF01889041
Henderson, J. M., J. D. Campbell, R. Olson, and R. C. Nelson. “Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis.Gastrointest Radiol 13, no. 2 (1988): 129–34. https://doi.org/10.1007/BF01889041.
Henderson JM, Campbell JD, Olson R, Nelson RC. Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis. Gastrointest Radiol. 1988;13(2):129–34.
Henderson, J. M., et al. “Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis.Gastrointest Radiol, vol. 13, no. 2, 1988, pp. 129–34. Pubmed, doi:10.1007/BF01889041.
Henderson JM, Campbell JD, Olson R, Nelson RC. Role of computed tomography in screening for hepatocellular carcinoma in patients with cirrhosis. Gastrointest Radiol. 1988;13(2):129–134.

Published In

Gastrointest Radiol

DOI

ISSN

0364-2356

Publication Date

1988

Volume

13

Issue

2

Start / End Page

129 / 134

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Nuclear Medicine & Medical Imaging
  • Liver Neoplasms
  • Liver Cirrhosis, Alcoholic
  • Liver Cirrhosis
  • Liver
  • Humans
  • Carcinoma, Hepatocellular
  • Biopsy
  • 3202 Clinical sciences