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Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience.

Publication ,  Journal Article
Schindera, ST; Nelson, RC; DeLong, DM; Jaffe, TA; Merkle, EM; Paulson, EK; Thomas, J
Published in: Radiology
May 2007

PURPOSE: To prospectively determine quantitatively and qualitatively the timing of maximal enhancement of the normal small-bowel wall by using contrast material-enhanced multi-detector row computed tomography (CT). MATERIALS AND METHODS: This HIPAA-compliant study was approved by the institutional review board. After information on radiation risk was given, written informed consent was obtained from 25 participants with no history of small-bowel disease (mean age, 58 years; 19 men) who had undergone single-level dynamic CT. Thirty seconds after the intravenous administration of contrast material, a serial dynamic acquisition, consisting of 10 images obtained 5 seconds apart, was performed. Enhancement measurements were obtained over time from the small-bowel wall and the aorta. Three independent readers qualitatively assessed small-bowel conspicuity. Quantitative and qualitative data were analyzed during the arterial phase, the enteric phase (which represented peak small-bowel mural enhancement), and the venous phase. Statistical analysis included paired Student t test and Wilcoxon signed rank test with Bonferroni correction. A P value less than .05 was used to indicate a significant difference. RESULTS: The mean time to peak enhancement of the small-bowel wall was 49.3 seconds +/- 7.7 (standard deviation) and 13.5 seconds +/- 7.6 after peak aortic enhancement. Enhancement values were highest during the enteric phase (P < .05). Regarding small-bowel conspicuity, images obtained during the enteric phase were most preferred qualitatively; there was a significant difference between the enteric and arterial phases (P < .001) but not between the enteric and venous phases (P = .18). CONCLUSION: At multi-detector row CT, peak mural enhancement of the normal small bowel occurs on average about 50 seconds after intravenous administration of contrast material or 14 seconds after peak aortic enhancement.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2007

Volume

243

Issue

2

Start / End Page

438 / 444

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiographic Image Enhancement
  • Pilot Projects
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Intestine, Small
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Schindera, S. T., Nelson, R. C., DeLong, D. M., Jaffe, T. A., Merkle, E. M., Paulson, E. K., & Thomas, J. (2007). Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience. Radiology, 243(2), 438–444. https://doi.org/10.1148/radiol.2432060534
Schindera, Sebastian T., Rendon C. Nelson, David M. DeLong, Tracy A. Jaffe, Elmar M. Merkle, Erik K. Paulson, and John Thomas. “Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience.Radiology 243, no. 2 (May 2007): 438–44. https://doi.org/10.1148/radiol.2432060534.
Schindera ST, Nelson RC, DeLong DM, Jaffe TA, Merkle EM, Paulson EK, et al. Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience. Radiology. 2007 May;243(2):438–44.
Schindera, Sebastian T., et al. “Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience.Radiology, vol. 243, no. 2, May 2007, pp. 438–44. Pubmed, doi:10.1148/radiol.2432060534.
Schindera ST, Nelson RC, DeLong DM, Jaffe TA, Merkle EM, Paulson EK, Thomas J. Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience. Radiology. 2007 May;243(2):438–444.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2007

Volume

243

Issue

2

Start / End Page

438 / 444

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiographic Image Enhancement
  • Pilot Projects
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Intestine, Small
  • Humans