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Serum markers of cerebral ischemia.

Publication ,  Journal Article
Laskowitz, DT; Grocott, H; Hsia, A; Copeland, KR
Published in: J Stroke Cerebrovasc Dis
1998

Rapid diagnosis and management of stroke patients is becoming increasingly important with the emergence of new interventional strategies for acute cerebral ischemia. A biochemical surrogate of cerebral ischemia, rapidly detectable in the serum before radiological diagnosis, might have clinical utility in the setting of acute stroke, high-risk cardiovascular procedures, and subarachnoid hemorrhage. Such a marker might also aid in the neurological prognosis of anoxic brain injury. Several serum markers have been evaluated in acute cerebral ischemia. These include neuronal enzymes such as neuron-specific enolase; markers of glial injury and activation, such as protein S100beta; and mediators of inflammation, such as interleukin-6. The clinical and preclinical data supporting the use of these biochemical surrogates of cerebral ischemia are reviewed.

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Published In

J Stroke Cerebrovasc Dis

DOI

ISSN

1052-3057

Publication Date

1998

Volume

7

Issue

4

Start / End Page

234 / 241

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

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Laskowitz, D. T., Grocott, H., Hsia, A., & Copeland, K. R. (1998). Serum markers of cerebral ischemia. J Stroke Cerebrovasc Dis, 7(4), 234–241. https://doi.org/10.1016/s1052-3057(98)80032-3
Laskowitz, D. T., H. Grocott, A. Hsia, and K. R. Copeland. “Serum markers of cerebral ischemia.J Stroke Cerebrovasc Dis 7, no. 4 (1998): 234–41. https://doi.org/10.1016/s1052-3057(98)80032-3.
Laskowitz DT, Grocott H, Hsia A, Copeland KR. Serum markers of cerebral ischemia. J Stroke Cerebrovasc Dis. 1998;7(4):234–41.
Laskowitz, D. T., et al. “Serum markers of cerebral ischemia.J Stroke Cerebrovasc Dis, vol. 7, no. 4, 1998, pp. 234–41. Pubmed, doi:10.1016/s1052-3057(98)80032-3.
Laskowitz DT, Grocott H, Hsia A, Copeland KR. Serum markers of cerebral ischemia. J Stroke Cerebrovasc Dis. 1998;7(4):234–241.
Journal cover image

Published In

J Stroke Cerebrovasc Dis

DOI

ISSN

1052-3057

Publication Date

1998

Volume

7

Issue

4

Start / End Page

234 / 241

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences