Drug-induced lung injury.

Journal Article (Journal Article;Review)

Lung injury is an increasing cause of morbidity and mortality in patients treated with cytotoxic and noncytotoxic drugs. Prompt diagnosis is important because early drug-induced lung injury will often regress with the cessation of therapy. Diagnosis requires a high index of suspicion because infection, radiation pneumonitis, and recurrence of the underlying disease can manifest clinically and radiologically in a similar manner. Because the lungs have only a limited number of histopathologic responses to injury, including pulmonary edema/diffuse alveolar damage, NSIP, BOOP, EP, and pulmonary hemorrhage, knowledge of these manifestations and the corresponding radiologic manifestations can often be useful in suggesting a diagnosis of drug-induced lung injury. An understanding of the drugs most commonly associated with lung injury can also facilitate diagnosis.

Full Text

Duke Authors

Cited Authors

  • Erasmus, JJ; McAdams, HP; Rossi, SE

Published Date

  • January 2002

Published In

Volume / Issue

  • 37 / 1

Start / End Page

  • 72 - 81

PubMed ID

  • 11987768

International Standard Serial Number (ISSN)

  • 0037-198X

Digital Object Identifier (DOI)

  • 10.1053/sroe.2002.0000


  • eng

Conference Location

  • United States