Drug-induced lung injury.


Journal Article (Review)

Lung injury is an increasing cause of morbidity and mortality in patients treated with cytotoxic and noncytotoxic drugs. Prompt diagnosis is important because early drug-induced lung injury will often regress with the cessation of therapy. Diagnosis requires a high index of suspicion because infection, radiation pneumonitis, and recurrence of the underlying disease can manifest clinically and radiologically in a similar manner. Because the lungs have only a limited number of histopathologic responses to injury, including pulmonary edema/diffuse alveolar damage, NSIP, BOOP, EP, and pulmonary hemorrhage, knowledge of these manifestations and the corresponding radiologic manifestations can often be useful in suggesting a diagnosis of drug-induced lung injury. An understanding of the drugs most commonly associated with lung injury can also facilitate diagnosis.

Full Text

Duke Authors

Cited Authors

  • Erasmus, JJ; McAdams, HP; Rossi, SE

Published Date

  • January 2002

Published In

Volume / Issue

  • 37 / 1

Start / End Page

  • 72 - 81

PubMed ID

  • 11987768

Pubmed Central ID

  • 11987768

International Standard Serial Number (ISSN)

  • 0037-198X

Digital Object Identifier (DOI)

  • 10.1053/sroe.2002.0000


  • eng

Conference Location

  • United States