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Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax.

Publication ,  Journal Article
Patz, EF; Erasmus, JJ; McAdams, HP; Connolly, JE; Marom, EM; Goodman, PC; Leder, RA; Keogan, MT; Herndon, JE
Published in: Radiology
July 1999

PURPOSE: To determine whether contrast material-enhanced helical computed tomography (CT) of the thorax and upper abdomen changes the tumor stage and management compared with nonenhanced helical CT in patients with newly diagnosed lung cancer. MATERIALS AND METHODS: During 15 months, any patient in whom lung cancer was strongly suspected or newly diagnosed and who was scheduled for thoracic CT was considered eligible for the study. All patients underwent nonenhanced thoracic helical CT from the lung apices through the adrenal glands and then contrast-enhanced thoracic helical CT from the lung apices through the entire liver. Each study was read independently, and the thoracic radiologic stage was determined. Tissue sampling was performed and the final pathologic stage assigned. RESULTS: Ninety-six patients had a final pathologic diagnosis of lung cancer. There was agreement in stage between the nonenhanced and contrast-enhanced examinations in 92 of the 96 patients. In three patients, the tumor stage at nonehanced CT increased at contrast-enhanced CT, from IA to IIA (n = 1), IIB to IV (n = 1), and IIIB to IV (n = 1). In one patient, the tumor stage decreased from IIIB to IIB. There was no substantial change in management of any patient. CONCLUSION: The results suggest that contrast-enhanced thoracic CT through the liver for staging lung cancer rarely changes the tumor stage determined with nonenhanced CT through the adrenal glands and does not substantially influence management decisions.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

July 1999

Volume

212

Issue

1

Start / End Page

56 / 60

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Neoplasm Staging
  • Middle Aged
  • Male
  • Lymphatic Metastasis
  • Lymph Nodes
  • Lung Neoplasms
  • Lung
 

Citation

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Patz, E. F., Erasmus, J. J., McAdams, H. P., Connolly, J. E., Marom, E. M., Goodman, P. C., … Herndon, J. E. (1999). Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax. Radiology, 212(1), 56–60. https://doi.org/10.1148/radiology.212.1.r99jl1956
Patz, E. F., J. J. Erasmus, H. P. McAdams, J. E. Connolly, E. M. Marom, P. C. Goodman, R. A. Leder, M. T. Keogan, and J. E. Herndon. “Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax.Radiology 212, no. 1 (July 1999): 56–60. https://doi.org/10.1148/radiology.212.1.r99jl1956.
Patz EF, Erasmus JJ, McAdams HP, Connolly JE, Marom EM, Goodman PC, et al. Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax. Radiology. 1999 Jul;212(1):56–60.
Patz, E. F., et al. “Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax.Radiology, vol. 212, no. 1, July 1999, pp. 56–60. Pubmed, doi:10.1148/radiology.212.1.r99jl1956.
Patz EF, Erasmus JJ, McAdams HP, Connolly JE, Marom EM, Goodman PC, Leder RA, Keogan MT, Herndon JE. Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax. Radiology. 1999 Jul;212(1):56–60.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

July 1999

Volume

212

Issue

1

Start / End Page

56 / 60

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Radiographic Image Enhancement
  • Nuclear Medicine & Medical Imaging
  • Neoplasm Staging
  • Middle Aged
  • Male
  • Lymphatic Metastasis
  • Lymph Nodes
  • Lung Neoplasms
  • Lung