Positron emission tomography with fluoro-2-deoxy-D-glucose (FDG-PET) in the staging of post transplant lymphoproliferative disorder in lung transplant recipients.
Posttransplantation lymphoproliferative disorder (PTLD) is a histologic heterogeneous disease that complicates 4 to 8% of lung transplant recipients. Disease extent is an important prognostic factor and may affect therapy. Positron emission tomography with fluoro-2-deoxy-D-glucose (FDG-PET) has proven useful for staging high-grade lymphomas but is less accurate for staging low-grade and extranodal lymphoma. This study examined our initial experience using FDG-PET imaging to stage lung transplant recipients with posttransplantation lymphoproliferative disorder. FDG can show foci of uptake, particularly in extrathoracic sites, not seen by conventional imaging, which allows more accurate staging of disease thereby yielding useful prognostic information and guiding therapy.
Duke Scholars
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Related Subject Headings
- Tomography, Emission-Computed
- Retrospective Studies
- Radiopharmaceuticals
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Lymphoproliferative Disorders
- Lung Transplantation
- Humans
- Fluorodeoxyglucose F18
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Tomography, Emission-Computed
- Retrospective Studies
- Radiopharmaceuticals
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Lymphoproliferative Disorders
- Lung Transplantation
- Humans
- Fluorodeoxyglucose F18