Conjugated polyelectrolyte capsules: Light-activated antimicrobial micro "roach Motels"

Microcapsules consisting of alternating layers of oppositely charged poly(phenylene ethynylene)-type conjugated polyelectrolytes (CPEs) were prepared via layer-by-layer deposition onto MnCO 3 template particles followed by dissolution of the template particles using an ethylenediaminetetraacetate solution. The resulting microcapsules exhibit bright-green fluorescence emission characteristics of the CPEs. Strong antimicrobial activity was observed upon mixing of polyelectrolyte capsules with Cobetia marina or Pseudomonas aeruginosa followed by white-light irradiation. It was demonstrated that the materials act as highly effective light-activated micro "Roach Motels" with greater than 95% kill after exposure to ∼1 h of white light. © 2008 American Chemical Society.

Full Text

Duke Authors

Cited Authors

  • Corbitt, TS; Sommer, JR; Chemburu, S; Ogawa, K; Ista, LK; Lopez, GP; Whitten, DG; Schanze, KS

Published Date

  • 2009

Published In

Volume / Issue

  • 1 / 1

Start / End Page

  • 48 - 52

International Standard Serial Number (ISSN)

  • 1944-8244

Digital Object Identifier (DOI)

  • 10.1021/am800096q

Citation Source

  • SciVal