Light-induced biocidal action of conjugated polyelectrolytes supported on colloids.


Journal Article

A series of water soluble, cationic conjugated polyelectrolytes (CPEs) with backbones based on a poly(phenylene ethynylene) repeat unit structure and tetraakylammonium side groups exhibit a profound light-induced biocidal effect. The present study examines the biocidal activity of the CPEs, correlating this activity with the photophysical properties of the polymers. The photophysical properties of the CPEs are studied in solution, and the results demonstrate that direct excitation produces a triplet excited-state in moderate yield, and the triplet is shown to be effective at sensitizing the production of singlet oxygen. Using the polymers in a format where they are physisorbed or covalently grafted to the surface of colloidal silica particles (5 and 30 microm diameter), we demonstrate that they exhibit light-activated biocidal activity, effectively killing Cobetia marina and Pseudomonas aeruginosa. The light-induced biocidal activity is also correlated with a requirement for oxygen suggesting that interfacial generation of singlet oxygen is the crucial step in the light-induced biocidal activity.

Full Text

Cited Authors

  • Chemburu, S; Corbitt, TS; Ista, LK; Ji, E; Fulghum, J; Lopez, GP; Ogawa, K; Schanze, KS; Whitten, DG

Published Date

  • October 2008

Published In

Volume / Issue

  • 24 / 19

Start / End Page

  • 11053 - 11062

PubMed ID

  • 18729335

Pubmed Central ID

  • 18729335

Electronic International Standard Serial Number (EISSN)

  • 1520-5827

International Standard Serial Number (ISSN)

  • 0743-7463

Digital Object Identifier (DOI)

  • 10.1021/la8016547


  • eng