Prenatal diagnosis using deletion studies in Duchenne muscular dystrophy.
Journal Article (Journal Article)
Accurate carrier testing and prenatal diagnosis in Duchenne muscular dystrophy (DMD) families is facilitated when an Xp21 deletion is found to be segregating within a family. We discuss the results of the DNA testing in two families, one in which DNA from affected males was available for study and the other in which no DNA from an affected male was available. Factors complicating the counselling of DMD deletion families are outlined.
Full Text
Duke Authors
Cited Authors
- Speer, MC; Pericak-Vance, MA; Yamaoka, LH; Koh, J; Hung, WY; Gaskell, PC; Vance, JM; Bartlett, RJ; Roses, AD
Published Date
- July 1988
Published In
Volume / Issue
- 8 / 6
Start / End Page
- 427 - 437
PubMed ID
- 3211845
Pubmed Central ID
- 3211845
International Standard Serial Number (ISSN)
- 0197-3851
Digital Object Identifier (DOI)
- 10.1002/pd.1970080607
Language
- eng
Conference Location
- England