Prenatal diagnosis using deletion studies in Duchenne muscular dystrophy.

Journal Article (Journal Article)

Accurate carrier testing and prenatal diagnosis in Duchenne muscular dystrophy (DMD) families is facilitated when an Xp21 deletion is found to be segregating within a family. We discuss the results of the DNA testing in two families, one in which DNA from affected males was available for study and the other in which no DNA from an affected male was available. Factors complicating the counselling of DMD deletion families are outlined.

Full Text

Duke Authors

Cited Authors

  • Speer, MC; Pericak-Vance, MA; Yamaoka, LH; Koh, J; Hung, WY; Gaskell, PC; Vance, JM; Bartlett, RJ; Roses, AD

Published Date

  • July 1988

Published In

Volume / Issue

  • 8 / 6

Start / End Page

  • 427 - 437

PubMed ID

  • 3211845

Pubmed Central ID

  • 3211845

International Standard Serial Number (ISSN)

  • 0197-3851

Digital Object Identifier (DOI)

  • 10.1002/pd.1970080607

Language

  • eng

Conference Location

  • England