Hereditary motor and sensory neuropathy, X-linked: a half century follow-up.

Journal Article (Journal Article)

The existence of an X-linked sensorimotor peripheral neuropathy has been debated. We reevaluated the original family, and present data on 13 affected males and 25 obligate or probable heterozygous females, documenting the devastating nature of the disease in the men and the extremely variable degree of clinical involvement in the carriers. Use of DNA probes indicates that the gene lies in the DXYS1-p58-1 region of the X-chromosome.

Full Text

Duke Authors

Cited Authors

  • Rozear, MP; Pericak-Vance, MA; Fischbeck, K; Stajich, JM; Gaskell, PC; Krendel, DA; Graham, DG; Dawson, DV; Roses, AD

Published Date

  • September 1987

Published In

Volume / Issue

  • 37 / 9

Start / End Page

  • 1460 - 1465

PubMed ID

  • 3476859

International Standard Serial Number (ISSN)

  • 0028-3878

Digital Object Identifier (DOI)

  • 10.1212/wnl.37.9.1460

Language

  • eng

Conference Location

  • United States