Hereditary motor and sensory neuropathy, X-linked: a half century follow-up.
Journal Article (Journal Article)
The existence of an X-linked sensorimotor peripheral neuropathy has been debated. We reevaluated the original family, and present data on 13 affected males and 25 obligate or probable heterozygous females, documenting the devastating nature of the disease in the men and the extremely variable degree of clinical involvement in the carriers. Use of DNA probes indicates that the gene lies in the DXYS1-p58-1 region of the X-chromosome.
Full Text
Duke Authors
Cited Authors
- Rozear, MP; Pericak-Vance, MA; Fischbeck, K; Stajich, JM; Gaskell, PC; Krendel, DA; Graham, DG; Dawson, DV; Roses, AD
Published Date
- September 1987
Published In
Volume / Issue
- 37 / 9
Start / End Page
- 1460 - 1465
PubMed ID
- 3476859
International Standard Serial Number (ISSN)
- 0028-3878
Digital Object Identifier (DOI)
- 10.1212/wnl.37.9.1460
Language
- eng
Conference Location
- United States