The role of apolipoprotein E in the nervous system.


Journal Article (Review)

Human apolipoprotein (apo)E, an important component of plasma lipoprotein metabolism, was recently linked to Alzheimer's disease. Of the three common apoE alleles, epsilon 4 has emerged as a major risk factor. This review summarizes the data leading to this conclusion and discusses possible mechanisms for apoE involvement based on recent biochemical studies.

Full Text

Duke Authors

Cited Authors

  • Weisgraber, KH; Roses, AD; Strittmatter, WJ

Published Date

  • April 1, 1994

Published In

Volume / Issue

  • 5 / 2

Start / End Page

  • 110 - 116

PubMed ID

  • 8044413

Pubmed Central ID

  • 8044413

International Standard Serial Number (ISSN)

  • 0957-9672


  • eng

Conference Location

  • England