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The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.

Publication ,  Journal Article
Taylor, WD; Züchner, S; Payne, ME; Messer, DF; Doty, TJ; MacFall, JR; Beyer, JL; Krishnan, KRR
Published in: Psychiatry Res
July 15, 2007

We examined the relationship between COMT Val158Met genotype and temporal lobe volumes, including the caudate as a control region. Thirty-one healthy subjects completed 1.5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes.

Duke Scholars

Published In

Psychiatry Res

DOI

ISSN

0165-1781

Publication Date

July 15, 2007

Volume

155

Issue

2

Start / End Page

173 / 177

Location

Ireland

Related Subject Headings

  • Valine
  • Temporal Lobe
  • Psychiatry
  • Polymorphism, Single Nucleotide
  • Middle Aged
  • Methionine
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Homozygote
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Taylor, W. D., Züchner, S., Payne, M. E., Messer, D. F., Doty, T. J., MacFall, J. R., … Krishnan, K. R. R. (2007). The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults. Psychiatry Res, 155(2), 173–177. https://doi.org/10.1016/j.pscychresns.2007.01.005
Taylor, Warren D., Stephan Züchner, Martha E. Payne, Denise F. Messer, Tracy J. Doty, James R. MacFall, John L. Beyer, and K Ranga R. Krishnan. “The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.Psychiatry Res 155, no. 2 (July 15, 2007): 173–77. https://doi.org/10.1016/j.pscychresns.2007.01.005.
Taylor WD, Züchner S, Payne ME, Messer DF, Doty TJ, MacFall JR, et al. The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults. Psychiatry Res. 2007 Jul 15;155(2):173–7.
Taylor, Warren D., et al. “The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.Psychiatry Res, vol. 155, no. 2, July 2007, pp. 173–77. Pubmed, doi:10.1016/j.pscychresns.2007.01.005.
Taylor WD, Züchner S, Payne ME, Messer DF, Doty TJ, MacFall JR, Beyer JL, Krishnan KRR. The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults. Psychiatry Res. 2007 Jul 15;155(2):173–177.
Journal cover image

Published In

Psychiatry Res

DOI

ISSN

0165-1781

Publication Date

July 15, 2007

Volume

155

Issue

2

Start / End Page

173 / 177

Location

Ireland

Related Subject Headings

  • Valine
  • Temporal Lobe
  • Psychiatry
  • Polymorphism, Single Nucleotide
  • Middle Aged
  • Methionine
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Homozygote