The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.

Journal Article (Journal Article)

We examined the relationship between COMT Val158Met genotype and temporal lobe volumes, including the caudate as a control region. Thirty-one healthy subjects completed 1.5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes.

Full Text

Duke Authors

Cited Authors

  • Taylor, WD; Züchner, S; Payne, ME; Messer, DF; Doty, TJ; MacFall, JR; Beyer, JL; Krishnan, KRR

Published Date

  • July 15, 2007

Published In

Volume / Issue

  • 155 / 2

Start / End Page

  • 173 - 177

PubMed ID

  • 17521892

Pubmed Central ID

  • PMC1950247

International Standard Serial Number (ISSN)

  • 0165-1781

Digital Object Identifier (DOI)

  • 10.1016/j.pscychresns.2007.01.005


  • eng

Conference Location

  • Ireland