The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.
Journal Article (Journal Article)
We examined the relationship between COMT Val158Met genotype and temporal lobe volumes, including the caudate as a control region. Thirty-one healthy subjects completed 1.5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes.
Full Text
Duke Authors
Cited Authors
- Taylor, WD; Züchner, S; Payne, ME; Messer, DF; Doty, TJ; MacFall, JR; Beyer, JL; Krishnan, KRR
Published Date
- July 15, 2007
Published In
Volume / Issue
- 155 / 2
Start / End Page
- 173 - 177
PubMed ID
- 17521892
Pubmed Central ID
- PMC1950247
International Standard Serial Number (ISSN)
- 0165-1781
Digital Object Identifier (DOI)
- 10.1016/j.pscychresns.2007.01.005
Language
- eng
Conference Location
- Ireland