Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging.


Journal Article

A line-scan echo planar spectroscopic imaging (LSEPSI) sequence was used to serially acquire spectra from 4,096 voxels every 6.4 s throughout the breasts of nine female subjects in vivo. Data from the serial acquisitions were analyzed to determine the potential of the technique to characterize temperature changes using either the water frequency alone or the water-methylene frequency difference. Fluctuations of the apparent temperature change under these conditions of no heating were smallest using the water-methylene frequency difference, most probably due to a substantial reduction of motion effects both within and without the imaged plane. The approach offers considerable advantages over other methods for temperature change monitoring in the breast with magnetic resonance but suffers from some limitations, including the unavailability of lipid and water resonances in some voxels as well as a surprisingly large distribution of water-methylene frequency differences, which may preclude absolute temperature measurement.

Full Text

Duke Authors

Cited Authors

  • McDannold, N; Barnes, AS; Rybicki, FJ; Oshio, K; Chen, N-K; Hynynen, K; Mulkern, RV

Published Date

  • December 2007

Published In

Volume / Issue

  • 58 / 6

Start / End Page

  • 1117 - 1123

PubMed ID

  • 18046702

Pubmed Central ID

  • 18046702

International Standard Serial Number (ISSN)

  • 0740-3194

Digital Object Identifier (DOI)

  • 10.1002/mrm.21322


  • eng

Conference Location

  • United States