Spatially selective T2 and T2 * measurement with line-scan echo-planar spectroscopic imaging.


Journal Article

Line-scan echo planar spectroscopic imaging (LSEPSI) is applied to quickly measure the T2 and T2* relaxation time constants in pre-selected 2D or 3D regions. Results from brain imaging studies at 3T suggest that the proposed method may prove valuable for both basic research (e.g., quantifying the changes of T2/T2* values in functional MRI with blood oxygenation level-dependent contrast) and clinical studies (e.g., measuring the T2' shortening due to iron deposition). The proposed spatially selective T2 and T2* mapping technique is especially well suited for studies, where T2/T2* quantification needs to be performed dynamically in a pre-selected 2D or 3D region.

Full Text

Cited Authors

  • Chen, N-K; Oshio, K; Panych, LP; Rybicki, FJ; Mulkern, RV

Published Date

  • November 2004

Published In

Volume / Issue

  • 171 / 1

Start / End Page

  • 90 - 96

PubMed ID

  • 15504686

Pubmed Central ID

  • 15504686

International Standard Serial Number (ISSN)

  • 1090-7807

Digital Object Identifier (DOI)

  • 10.1016/j.jmr.2004.08.004


  • eng

Conference Location

  • United States