Experimental transvitreal cyanoacrylate retinopexy in a primate model.

Journal Article (Journal Article)

We evaluated the use of transvitreal cyanoacrylate retinopexy in the treatment of experimental rhegmatogenous retinal detachment during vitreous surgery in the cynomolgus monkey. The chorioretinal adhesions produced with cyanoacrylate tissue adhesive as compared with those produced by transscleral retinal cryopexy were more rapid in onset as well as stronger. To test the efficacy of cyanoacrylate retinopexy further, a 360-degree peripheral retinectomy was created in five eyes with circumferential cyanoacrylate application to the posterior retinal edge. The cyanoacrylate retinopexy did not prevent the development of proliferative vitreoretinopathy with traction retinal detachment, but in three of the eyes the tissue adhesive continued to maintain retinal apposition to the retinal pigment epithelium at the retinotomy edge. Histologic examination of the retinas disclosed a foreign body reaction adjacent to the cyanoacrylate sites, but there was no evidence of any distant effects caused by the tissue adhesive.

Full Text

Duke Authors

Cited Authors

  • Hida, T; Sheta, SM; Proia, AD; McCuen, BW

Published Date

  • June 15, 1987

Published In

Volume / Issue

  • 103 / 6

Start / End Page

  • 782 - 789

PubMed ID

  • 3591878

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/s0002-9394(14)74394-6


  • eng

Conference Location

  • United States