The renin-angiotensin system: it's all in your head.

Journal Article (Journal Article)

Components of the renin-angiotensin system (RAS) are expressed in a number of areas in the brain involved in cardiovascular control. However, it has been difficult to link RAS actions in circumscribed brain regions to specific physiological functions. In a study appearing in this issue of the JCI, Sakai and associates use a combination of sophisticated transgenic techniques and stereotaxic microinjection of recombinant viral vectors to demonstrate a pivotal role in the regulation of thirst and salt appetite of angiotensin II generated in the subfornical organ in the brain (see the related article beginning on page 1088).

Full Text

Duke Authors

Cited Authors

  • Parsons, KK; Coffman, TM

Published Date

  • April 2007

Published In

Volume / Issue

  • 117 / 4

Start / End Page

  • 873 - 876

PubMed ID

  • 17404616

Pubmed Central ID

  • PMC1838953

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/JCI31856


  • eng

Conference Location

  • United States