The renin-angiotensin system: it's all in your head.
Published
Journal Article
Components of the renin-angiotensin system (RAS) are expressed in a number of areas in the brain involved in cardiovascular control. However, it has been difficult to link RAS actions in circumscribed brain regions to specific physiological functions. In a study appearing in this issue of the JCI, Sakai and associates use a combination of sophisticated transgenic techniques and stereotaxic microinjection of recombinant viral vectors to demonstrate a pivotal role in the regulation of thirst and salt appetite of angiotensin II generated in the subfornical organ in the brain (see the related article beginning on page 1088).
Full Text
Duke Authors
Cited Authors
- Parsons, KK; Coffman, TM
Published Date
- April 2007
Published In
Volume / Issue
- 117 / 4
Start / End Page
- 873 - 876
PubMed ID
- 17404616
Pubmed Central ID
- 17404616
International Standard Serial Number (ISSN)
- 0021-9738
Digital Object Identifier (DOI)
- 10.1172/JCI31856
Language
- eng
Conference Location
- United States