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Pharmacologic adjuncts during mechanical ventilation.

Publication ,  Journal Article
Que, LG; Tony Huang, YC
Published in: Semin Respir Crit Care Med
2000

Despite recent advances in technology, the mortality rate for patients suffering from adult respiratory distress syndrome remains in the range of 40-50%. This high mortality rate may be in part related to complications from ventilator management, such as ventilator-induced lung injury. In these patients, adjunct therapies aiming at ameliorating ventilator-induced lung injury are being developed. This article discusses the rationale for use of pharmacologic adjunct therapies, including inhaled nitric oxide, surfactant replacement therapy, antioxidants, prostaglandins, and corticosteroids, in patients with acute lung injury, and reviews the effectiveness of these agents in human clinical trials to date.

Duke Scholars

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Published In

Semin Respir Crit Care Med

DOI

ISSN

1069-3424

Publication Date

2000

Volume

21

Issue

3

Start / End Page

223 / 232

Location

United States

Related Subject Headings

  • Respiratory System
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

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Que, L. G., & Tony Huang, Y. C. (2000). Pharmacologic adjuncts during mechanical ventilation. Semin Respir Crit Care Med, 21(3), 223–232. https://doi.org/10.1055/s-2000-9848
Que, L. G., and Y. C. Tony Huang. “Pharmacologic adjuncts during mechanical ventilation.Semin Respir Crit Care Med 21, no. 3 (2000): 223–32. https://doi.org/10.1055/s-2000-9848.
Que LG, Tony Huang YC. Pharmacologic adjuncts during mechanical ventilation. Semin Respir Crit Care Med. 2000;21(3):223–32.
Que, L. G., and Y. C. Tony Huang. “Pharmacologic adjuncts during mechanical ventilation.Semin Respir Crit Care Med, vol. 21, no. 3, 2000, pp. 223–32. Pubmed, doi:10.1055/s-2000-9848.
Que LG, Tony Huang YC. Pharmacologic adjuncts during mechanical ventilation. Semin Respir Crit Care Med. 2000;21(3):223–232.
Journal cover image

Published In

Semin Respir Crit Care Med

DOI

ISSN

1069-3424

Publication Date

2000

Volume

21

Issue

3

Start / End Page

223 / 232

Location

United States

Related Subject Headings

  • Respiratory System
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology