Severe factor V deficiency presenting with intracranial haemorrhage during gestation.

Journal Article (Journal Article)

We present a case of intracranial haemorrhage detected by ultrasound at 36 weeks gestation in a foetus who was ultimately diagnosed with severe factor V deficiency. An abnormality of the foetal heart rate, auscultated at a routine antenatal visit, prompted an investigation that led to an ultrasound examination and detection of an intracranial haemorrhage and low amniotic fluid volume. An intrauterine foetal demise was averted. The clinical scenario in this case raises the issue of how often a stillbirth with intracranial haemorrhage may result from unrecognized factor deficiency.

Full Text

Duke Authors

Cited Authors

  • Ellestad, SC; Zimmerman, SA; Thornburg, C; Mitchell, TE; Swamy, GK; James, AH

Published Date

  • July 2007

Published In

Volume / Issue

  • 13 / 4

Start / End Page

  • 432 - 434

PubMed ID

  • 17610562

International Standard Serial Number (ISSN)

  • 1351-8216

Digital Object Identifier (DOI)

  • 10.1111/j.1365-2516.2007.01469.x


  • eng

Conference Location

  • England