Current multicentre studies with the excimer laser: design and aims.

Journal Article (Clinical Trial;Journal Article;Review)

Excimer laser ablation to remove atherosclerotic plaque has been used for over a decade as a methodology to treat cardiovascular disease. Improvements in the technique and technology of excimer laser angioplasty, coupled with the recognition of new clinical opportunities for this treatment modality, have resulted in a resurgence of interest in the laser. Three clinical trials are now being conducted to explore potential applications, including the LARS trial of excimer laser versus balloon angioplasty to treat in-stent restenosis, the PELA trial of excimer laser angioplasty in occluded superficial femoral artery disease, and the LACI trial of excimer laser angioplasty in limb-threatening ischaemia. This article describes the rationale and objectives of these new approaches to some of the more challenging problems in cardiovascular disease.

Full Text

Duke Authors

Cited Authors

  • Tcheng, JE; Volkert-Noethen, AA

Published Date

  • 2001

Published In

Volume / Issue

  • 16 / 2

Start / End Page

  • 122 - 129

PubMed ID

  • 11484753

International Standard Serial Number (ISSN)

  • 0268-8921

Digital Object Identifier (DOI)

  • 10.1007/pl00011341


  • eng

Conference Location

  • England