Effects of diet and sodium intake on blood pressure: subgroup analysis of the DASH-sodium trial.


Journal Article

BACKGROUND: Initial findings from the Dietary Approaches to Stop Hypertension (DASH)-Sodium Trial demonstrated that reduction of sodium intake in two different diets decreased blood pressure in participants with and without hypertension. OBJECTIVE: To determine effects on blood pressure of reduced sodium intake and the DASH diet in additional subgroups. DESIGN: Randomized feeding study. SETTING: Four clinical centers and a coordinating center. PARTICIPANTS: 412 adults with untreated systolic blood pressure of 120 to 160 mm Hg and diastolic blood pressure of 80 to 95 mm Hg. INTERVENTION: Participants followed the DASH diet or a control (typical U.S.) diet for three consecutive 30-day feeding periods, during which sodium intake (50, 100, and 150 mmol/d at 2100 kcal) varied according to a randomly assigned sequence. Body weight was maintained. MEASUREMENTS: Systolic and diastolic blood pressure. RESULTS: In all subgroups, the DASH diet and reduced sodium intake were each associated with significant decreases in blood pressure; these two factors combined produced the greatest reductions. Among nonhypertensive participants who received the control diet, lower (vs. higher) sodium intake decreased blood pressure by 7.0/3.8 mm Hg in those older than 45 years of age (P < 0.001) and by 3.7/1.5 mm Hg in those 45 years of age or younger (P < 0.05). CONCLUSION: The DASH diet plus reduced sodium intake is recommended to control blood pressure in diverse subgroups.

Full Text

Duke Authors

Cited Authors

  • Vollmer, WM; Sacks, FM; Ard, J; Appel, LJ; Bray, GA; Simons-Morton, DG; Conlin, PR; Svetkey, LP; Erlinger, TP; Moore, TJ; Karanja, N; DASH-Sodium Trial Collaborative Research Group,

Published Date

  • December 18, 2001

Published In

Volume / Issue

  • 135 / 12

Start / End Page

  • 1019 - 1028

PubMed ID

  • 11747380

Pubmed Central ID

  • 11747380

International Standard Serial Number (ISSN)

  • 0003-4819

Digital Object Identifier (DOI)

  • 10.7326/0003-4819-135-12-200112180-00005


  • eng

Conference Location

  • United States