Effects of individual components of multiple behavior changes: the PREMIER trial.
OBJECTIVES: To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes. METHODS: We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants. RESULTS: In multivariate models omitting weight, predicted SBP reductions ranged from (1)/2 to 1(1)/2 mm Hg for reduced urinary sodium, improved fitness, and adherence to the DASH diet (except sodium at 18 months). With weight included, only fitness change additionally predicted SBP at 18 months. CONCLUSIONS: Several lifestyle behavior changes are important for BP lowering, but are difficult to detect when weight is included in multivariate models.
Obarzanek, E; Vollmer, WM; Lin, P-H; Cooper, LS; Young, DR; Ard, JD; Stevens, VJ; Simons-Morton, DG; Svetkey, LP; Harsha, DW; Elmer, PJ; Appel, LJ
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