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Weight loss during the intensive intervention phase of the weight-loss maintenance trial.

Publication ,  Journal Article
Hollis, JF; Gullion, CM; Stevens, VJ; Brantley, PJ; Appel, LJ; Ard, JD; Champagne, CM; Dalcin, A; Erlinger, TP; Funk, K; Laferriere, D ...
Published in: Am J Prev Med
August 2008

BACKGROUND: To improve methods for long-term weight management, the Weight Loss Maintenance (WLM) trial, a four-center randomized trial, was conducted to compare alternative strategies for maintaining weight loss over a 30-month period. This paper describes methods and results for the initial 6-month weight-loss program (Phase I). METHODS: Eligible adults were aged > or =25, overweight or obese (BMI=25-45 kg/m2), and on medications for hypertension and/or dyslipidemia. Anthropomorphic, demographic, and psychosocial measures were collected at baseline and 6 months. Participants (n=1685) attended 20 weekly group sessions to encourage calorie restriction, moderate-intensity physical activity, and the DASH (dietary approaches to stop hypertension) dietary pattern. Weight-loss predictors with missing data were replaced by multiple imputation. RESULTS: Participants were 44% African American and 67% women; 79% were obese (BMI> or =30), 87% were taking anti-hypertensive medications, and 38% were taking antidyslipidemia medications. Participants attended an average of 72% of 20 group sessions. They self-reported 117 minutes of moderate-intensity physical activity per week, kept 3.7 daily food records per week, and consumed 2.9 servings of fruits and vegetables per day. The Phase-I follow-up rate was 92%. Mean (SD) weight change was -5.8 kg (4.4), and 69% lost at least 4 kg. All race-gender subgroups lost substantial weight: African-American men (-5.4 kg +/- 7.7); African-American women (-4.1 kg +/- 2.9); non-African-American men (-8.5 kg +/- 12.9); and non-African-American women (-5.8 kg +/- 6.1). Behavioral measures (e.g., diet records and physical activity) accounted for most of the weight-loss variation, although the association between behavioral measures and weight loss differed by race and gender groups. CONCLUSIONS: The WLM behavioral intervention successfully achieved clinically significant short-term weight loss in a diverse population of high-risk patients.

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Published In

Am J Prev Med

DOI

ISSN

0749-3797

Publication Date

August 2008

Volume

35

Issue

2

Start / End Page

118 / 126

Location

Netherlands

Related Subject Headings

  • Weight Loss
  • Public Health
  • Patient Compliance
  • Overweight
  • Obesity
  • Middle Aged
  • Male
  • Humans
  • Female
  • Exercise
 

Citation

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Hollis, J. F., Gullion, C. M., Stevens, V. J., Brantley, P. J., Appel, L. J., Ard, J. D., … Weight Loss Maintenance Trial Research Group, . (2008). Weight loss during the intensive intervention phase of the weight-loss maintenance trial. Am J Prev Med, 35(2), 118–126. https://doi.org/10.1016/j.amepre.2008.04.013
Hollis, Jack F., Christina M. Gullion, Victor J. Stevens, Phillip J. Brantley, Lawrence J. Appel, Jamy D. Ard, Catherine M. Champagne, et al. “Weight loss during the intensive intervention phase of the weight-loss maintenance trial.Am J Prev Med 35, no. 2 (August 2008): 118–26. https://doi.org/10.1016/j.amepre.2008.04.013.
Hollis JF, Gullion CM, Stevens VJ, Brantley PJ, Appel LJ, Ard JD, et al. Weight loss during the intensive intervention phase of the weight-loss maintenance trial. Am J Prev Med. 2008 Aug;35(2):118–26.
Hollis, Jack F., et al. “Weight loss during the intensive intervention phase of the weight-loss maintenance trial.Am J Prev Med, vol. 35, no. 2, Aug. 2008, pp. 118–26. Pubmed, doi:10.1016/j.amepre.2008.04.013.
Hollis JF, Gullion CM, Stevens VJ, Brantley PJ, Appel LJ, Ard JD, Champagne CM, Dalcin A, Erlinger TP, Funk K, Laferriere D, Lin P-H, Loria CM, Samuel-Hodge C, Vollmer WM, Svetkey LP, Weight Loss Maintenance Trial Research Group. Weight loss during the intensive intervention phase of the weight-loss maintenance trial. Am J Prev Med. 2008 Aug;35(2):118–126.
Journal cover image

Published In

Am J Prev Med

DOI

ISSN

0749-3797

Publication Date

August 2008

Volume

35

Issue

2

Start / End Page

118 / 126

Location

Netherlands

Related Subject Headings

  • Weight Loss
  • Public Health
  • Patient Compliance
  • Overweight
  • Obesity
  • Middle Aged
  • Male
  • Humans
  • Female
  • Exercise