Hypertension, chronic kidney disease, and the development of cardiovascular risk: a joint primacy.

Journal Article (Journal Article)

Patients with chronic kidney disease (CKD) have an inordinate risk of cardiovascular disease. In addition to the metabolic state of uremia, the CKD-associated risk is partly explainable by unique cofactors such as dyslipidemia, systemic inflammation, and exposures that occur during renal replacement therapies. However, the comorbid condition of hypertension also enhances risk in patients with CKD. New observations suggest that diminished glomerular filtration rate and hypertension share primacy in the development of cardiovascular illness.

Full Text

Duke Authors

Cited Authors

  • Middleton, JP; Pun, PH

Published Date

  • May 2010

Published In

Volume / Issue

  • 77 / 9

Start / End Page

  • 753 - 755

PubMed ID

  • 20393488

Electronic International Standard Serial Number (EISSN)

  • 1523-1755

Digital Object Identifier (DOI)

  • 10.1038/ki.2010.19


  • eng

Conference Location

  • United States