A simplified method for monitoring the cytochrome aa3 redox state in bilateral cortical areas of unanesthetized cats.


Journal Article

We describe a versatile optical system that enables the simultaneous monitoring of the redox state of cytochrome c oxidase (cytochrome aa3) in two homologous cortical areas under chronically implanted windows in cats. A single light source, broad bandpass primary filters, light-conducting rods, and narrow-bandpass interference detecting filters are employed. We observed reproducible responses of the cytochrome redox state and blood volume to carotid occlusion and terminal anoxia during anesthesia, and to graded doses of pentobarbital in awake animals.

Full Text

Duke Authors

Cited Authors

  • Vern, BA; Schuette, WH; Juel, VC; Radulovacki, M

Published Date

  • July 7, 1987

Published In

Volume / Issue

  • 415 / 1

Start / End Page

  • 188 - 193

PubMed ID

  • 3040173

Pubmed Central ID

  • 3040173

International Standard Serial Number (ISSN)

  • 0006-8993

Digital Object Identifier (DOI)

  • 10.1016/0006-8993(87)90286-1


  • eng

Conference Location

  • Netherlands