Interhemispheric synchrony of slow oscillations of cortical blood volume and cytochrome aa3 redox state in unanesthetized rabbits.
Journal Article (Journal Article)
In order to study spontaneous, slow oscillations of regional oxidative metabolism and blood flow in the normal, unanesthetized cortex, adult rabbits were implanted with bilateral cortical windows and electrodes for polysomnography. Relative changes in the cortical intramitochondrial redox state of cytochrome aa3 (CYT) and blood volume (CBV) were monitored by dual-wavelength reflectance spectrophotometry. Continuous, non-stationary oscillations (< 0.5 Hz) of both CYT and CBV were observed during waking and non-REM sleep. Cross-correlation analysis revealed a predominant interhemispheric synchrony of these oscillations which were unrelated to the heart rate, breathing, or electrocorticogram pattern. These findings suggest a dynamic linkage of slowly varying metabolic and vascular processes between unanesthetized cortical regions of 50 mm2 surface area.
Full Text
Duke Authors
Cited Authors
- Vern, BA; Leheta, BJ; Juel, VC; LaGuardia, J; Graupe, P; Schuette, WH
Published Date
- November 14, 1997
Published In
Volume / Issue
- 775 / 1-2
Start / End Page
- 233 - 239
PubMed ID
- 9439851
International Standard Serial Number (ISSN)
- 0006-8993
Digital Object Identifier (DOI)
- 10.1016/s0006-8993(97)01028-7
Language
- eng
Conference Location
- Netherlands