Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses.
Publication
, Journal Article
Sunday, ME; Dorf, ME
Published in: J Immunol
August 1981
NP-O-Succinimide-induced cutaneous sensitivity (CS) responses can be adoptively transferred by NP-primed lymphoid cells into naive K-, I-, or D-compatible recipients. The distinct fine specificities of I- versus D-restricted T cell clones from various strains of mice suggested that presence of different idiotypic receptors on these T cell subsets. We now demonstrate that NP-O-Su immune lymphoid cells are composed of 2 T cell subsets with distinct antigen recognition patterns, as well as different Lyt 2 phenotypes. Thus, I-restricted cells respond to NP-coupled to a protein carrier but not to NP-coupled cells, whereas D-restricted clones react to NP-cells, but not to NP-protein conjugates.
Duke Scholars
Published In
J Immunol
ISSN
0022-1767
Publication Date
August 1981
Volume
127
Issue
2
Start / End Page
766 / 768
Location
United States
Related Subject Headings
- T-Lymphocytes
- Succinimides
- Phenylacetates
- Nitrophenols
- Mice, Inbred C57BL
- Mice
- Lymph Nodes
- Immunology
- Hypersensitivity, Delayed
- Haptens
Citation
APA
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ICMJE
MLA
NLM
Sunday, M. E., & Dorf, M. E. (1981). Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. J Immunol, 127(2), 766–768.
Sunday, M. E., and M. E. Dorf. “Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses.” J Immunol 127, no. 2 (August 1981): 766–68.
Sunday ME, Dorf ME. Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. J Immunol. 1981 Aug;127(2):766–8.
Sunday, M. E., and M. E. Dorf. “Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses.” J Immunol, vol. 127, no. 2, Aug. 1981, pp. 766–68.
Sunday ME, Dorf ME. Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. J Immunol. 1981 Aug;127(2):766–768.
Published In
J Immunol
ISSN
0022-1767
Publication Date
August 1981
Volume
127
Issue
2
Start / End Page
766 / 768
Location
United States
Related Subject Headings
- T-Lymphocytes
- Succinimides
- Phenylacetates
- Nitrophenols
- Mice, Inbred C57BL
- Mice
- Lymph Nodes
- Immunology
- Hypersensitivity, Delayed
- Haptens