Electrochemical study of ion channel behavior in incorporated poly L-glutamate bilayer lipid membranes.

Journal Article (Journal Article)

The lipid layer membranes were fabricated on the glassy carbon electrode (GC) and demonstrated to be bilayer lipid membranes by impedance spectroscopy. The formation of incorporated poly L-glutamate bilayer lipid membrane was achieved. The ion channel behavior of the incorporated poly L-glutamate membrane was determined. When the stimulus calcium cations were added into the electrolyte, the ion channel was opened immediately and exhibited distinct channel current. Otherwise, the ion channel was closed. The cyclic voltammogram at the GC electrode coated with incorporated poly L-glutamate DMPC film response to calcium ion is very fast compared with that at the GC electrode coated only with DMPC film. Ion channel current is not dependent on the time but on the concentration of calcium. The mechanism of the ion channel formation was investigated.

Full Text

Duke Authors

Cited Authors

  • Tong, Y; Wu, Z; Han, X; Wang, E

Published Date

  • June 2002

Published In

Volume / Issue

  • 34 / 3

Start / End Page

  • 185 - 191

PubMed ID

  • 12171068

International Standard Serial Number (ISSN)

  • 0145-479X

Digital Object Identifier (DOI)

  • 10.1023/a:1016031403141


  • eng

Conference Location

  • United States