Treatment and outcome of biopsy-proven fulminant myocarditis in adults.

Journal Article (Letter)

Fulminant myocarditis may be rapidly fatal with severe haemodynamic compromise in previously healthy patients. We reviewed our experience with eight cases of biopsy-proven fulminant myocarditis (seven cases with lymphocytic myocarditis and one with eosinophilic myocarditis). Immunosuppression was given in seven out of eight cases. Mechanical circulatory support was required in 50% of the patients. Time from onset of illness to recovery of ventricular function varied from 12 to 17 days. All except one patient were alive at a mean follow-up of 4.4 years after the acute illness. Patients with acute fulminant myocarditis should be treated aggressively with immunosuppression and, if necessary, mechanical circulatory support during the first 2 to 3 weeks of the illness because of the reversible nature of this illness and good long-term prognosis.

Full Text

Duke Authors

Cited Authors

  • Chau, EMC; Chow, W-H; Chiu, CSW; Wang, E

Published Date

  • June 28, 2006

Published In

Volume / Issue

  • 110 / 3

Start / End Page

  • 405 - 406

PubMed ID

  • 16297469

International Standard Serial Number (ISSN)

  • 0167-5273

Digital Object Identifier (DOI)

  • 10.1016/j.ijcard.2005.07.082


  • eng

Conference Location

  • Netherlands