The Cushing Response: a case for a review of its role as a physiological reflex.
Journal Article (Journal Article;Review)
Despite a century of work on the subject, controversy still exists as to the physiological relevance of the Cushing response (CR), a state of raised systemic blood pressure and bradycardia associated with raised intracranial pressure. The alternative that has been proposed to the classical belief of pre-terminal brainstem damage is of a baroreflex that attempts to maintain cerebral perfusion in response to situations of extreme elevations in intracranial pressure or brainstem ischemia. We report a patient with spontaneous subarachnoid haemorrhage who demonstrated CR, which was later seen to self-abort with an eventual good outcome. We review the existing literature and propose that our clinical case may provide further support for a physiological role of CR.
Full Text
Duke Authors
Cited Authors
- Wan, WH; Ang, BT; Wang, E
Published Date
- March 2008
Published In
Volume / Issue
- 15 / 3
Start / End Page
- 223 - 228
PubMed ID
- 18182296
International Standard Serial Number (ISSN)
- 0967-5868
Digital Object Identifier (DOI)
- 10.1016/j.jocn.2007.05.025
Language
- eng
Conference Location
- Scotland