Replicative senescence revisited.

Journal Article (Journal Article;Review)

Forty years after its discovery, replicative senescence remains a rich source of information about cell-cycle regulation and the progression from a normal to a transformed phenotype. Effectors of this growth-arrested state are being discovered at a great pace. This review discusses the latest findings on the players responsible for establishing replicative senescence, as well as the associated telomere shortening.

Full Text

Duke Authors

Cited Authors

  • Marcotte, R; Wang, E

Published Date

  • July 2002

Published In

Volume / Issue

  • 57 / 7

Start / End Page

  • B257 - B269

PubMed ID

  • 12084796

International Standard Serial Number (ISSN)

  • 1079-5006

Digital Object Identifier (DOI)

  • 10.1093/gerona/57.7.b257


  • eng

Conference Location

  • United States