Direct electron transfer between hemoglobin and a glassy carbon electrode facilitated by lipid-protected gold nanoparticles.

Published

Journal Article

We synthesized a kind of gold nanoparticle protected by a synthetic lipid (didodecyldimethylammonium bromide, DDAB). With the help of these gold nanoparticles, hemoglobin can exhibit a direct electron transfer (DET) reaction. The formal potential locates at -169 mV vs. Ag/AgCl. Spectral data indicated the hemoglobin on the electrode was not denatured. The lipid-protected gold nanoparticles were very stable (for at least 8 months). Their average diameter is 6.42 nm. It is the first time to use monolayer-protected nanoparticles to realize the direct electrochemistry of protein.

Full Text

Duke Authors

Cited Authors

  • Han, X; Cheng, W; Zhang, Z; Dong, S; Wang, E

Published Date

  • December 2002

Published In

Volume / Issue

  • 1556 / 2-3

Start / End Page

  • 273 - 277

PubMed ID

  • 12460686

Pubmed Central ID

  • 12460686

Electronic International Standard Serial Number (EISSN)

  • 1878-2434

International Standard Serial Number (ISSN)

  • 0006-3002

Digital Object Identifier (DOI)

  • 10.1016/s0005-2728(02)00372-9

Language

  • eng