Direct electron transfer between hemoglobin and a glassy carbon electrode facilitated by lipid-protected gold nanoparticles.
Journal Article (Journal Article)
We synthesized a kind of gold nanoparticle protected by a synthetic lipid (didodecyldimethylammonium bromide, DDAB). With the help of these gold nanoparticles, hemoglobin can exhibit a direct electron transfer (DET) reaction. The formal potential locates at -169 mV vs. Ag/AgCl. Spectral data indicated the hemoglobin on the electrode was not denatured. The lipid-protected gold nanoparticles were very stable (for at least 8 months). Their average diameter is 6.42 nm. It is the first time to use monolayer-protected nanoparticles to realize the direct electrochemistry of protein.
Full Text
Duke Authors
Cited Authors
- Han, X; Cheng, W; Zhang, Z; Dong, S; Wang, E
Published Date
- December 2, 2002
Published In
Volume / Issue
- 1556 / 2-3
Start / End Page
- 273 - 277
PubMed ID
- 12460686
International Standard Serial Number (ISSN)
- 0006-3002
Digital Object Identifier (DOI)
- 10.1016/s0005-2728(02)00372-9
Language
- eng
Conference Location
- Netherlands