Non-infectious aortitis: an important cause of severe aortic regurgitation.

Journal Article (Journal Article)

From 1995 to 2004, 13 patients with severe aortic regurgitation due to non-infectious aortitis underwent aortic valve surgery at our center. Twenty-eight operations (18 aortic valve replacements and 10 Bentall procedures including 1 aortic root replacement with a homograft) were performed due to a high incidence of prosthetic valve or valved conduit dehiscence (54%). Steroid therapy reduced the incidence of re-operation for anastomotic dehiscence within one year from 90% to 18%. Strategies to prevent dehiscence of the prosthetic aortic valve, which include institution of immunosuppression, replacement of the diseased aorta, and monitoring inflammatory indices, are discussed.

Full Text

Duke Authors

Cited Authors

  • Chau, EMC; Wang, E; Chiu, CSW; Chow, W-H

Published Date

  • June 2006

Published In

Volume / Issue

  • 14 / 3

Start / End Page

  • 177 - 182

PubMed ID

  • 16714691

Electronic International Standard Serial Number (EISSN)

  • 1816-5370

Digital Object Identifier (DOI)

  • 10.1177/021849230601400302


  • eng

Conference Location

  • England