Ion channel behavior of supported bilayer lipid membranes on a glassy carbon electrode.
Journal Article (Letter)
A new kind of solid substrate, a glassy carbon (GC) electrode, was selected to support lipid layer membranes. On the surface of the GC electrode, we made layers of didodecyldimethylammonium bromide (a synthetic lipid). From electrochemical impedance experiments, we demonstrated that the lipid layers on the GC electrode were bilayer lipid membranes. We studied the ion channel behavior of the supported bilayer lipid membrane. In the presence of perchlorate anions as the stimulus and ruthenium(II) complex cations as the marker ions, the lipid membrane channel was open and exhibited distinct channel current. The channel was in a closed state in the absence of perchlorate anions.
Full Text
Duke Authors
Cited Authors
- Wu, Z; Tang, J; Cheng, Z; Yang, X; Wang, E
Published Date
- December 15, 2000
Published In
Volume / Issue
- 72 / 24
Start / End Page
- 6030 - 6033
PubMed ID
- 11140773
International Standard Serial Number (ISSN)
- 0003-2700
Digital Object Identifier (DOI)
- 10.1021/ac000764x
Language
- eng
Conference Location
- United States