Ion channel behavior of supported bilayer lipid membranes on a glassy carbon electrode.

Published

Journal Article (Letter)

A new kind of solid substrate, a glassy carbon (GC) electrode, was selected to support lipid layer membranes. On the surface of the GC electrode, we made layers of didodecyldimethylammonium bromide (a synthetic lipid). From electrochemical impedance experiments, we demonstrated that the lipid layers on the GC electrode were bilayer lipid membranes. We studied the ion channel behavior of the supported bilayer lipid membrane. In the presence of perchlorate anions as the stimulus and ruthenium(II) complex cations as the marker ions, the lipid membrane channel was open and exhibited distinct channel current. The channel was in a closed state in the absence of perchlorate anions.

Full Text

Duke Authors

Cited Authors

  • Wu, Z; Tang, J; Cheng, Z; Yang, X; Wang, E

Published Date

  • December 15, 2000

Published In

Volume / Issue

  • 72 / 24

Start / End Page

  • 6030 - 6033

PubMed ID

  • 11140773

Pubmed Central ID

  • 11140773

International Standard Serial Number (ISSN)

  • 0003-2700

Digital Object Identifier (DOI)

  • 10.1021/ac000764x

Language

  • eng

Conference Location

  • United States