[Bcl-2 and bax expression in rat cerebral ischemic preconditioning].
Journal Article (English Abstract;Journal Article)
OBJECTIVE: To study the expression of apoptosis regulated genes bcl-2 and bax nocoprotein expression and its significance in rat cerebral ischemic preconditioning. METHODS: With immunohistochemical assay, bcl-2 and bax expression were studied in rat brains which were divided into four groups: the sham-operation control group, the cerebral ischemic group and the cerebral ischemic preconditioning group. RESULTS: Bcl-2 oncoprotein was induced in cerebral ischemic preconditioning control group. Bax oncoprotein expression had no obviously difference in four groups. CONCLUSIONS: The expression of bcl-2 and bax oncoprotein after sublethal ischemic preconditioning might be associated with the preconditioning protection against neuronal damage following subsequent lethal ischemia.
Full Text
Duke Authors
Cited Authors
- Wang, E; Guo, QL; Tan, XJ
Published Date
- June 28, 2001
Published In
Volume / Issue
- 26 / 3
Start / End Page
- 217 - 218
PubMed ID
- 12536685
International Standard Serial Number (ISSN)
- 1000-5625
Language
- chi
Conference Location
- China