Interferon inhibits the redistribution of cell surface components.

Journal Article

Interferon treatment impairs the ability of cells to redistribute cell surface receptors for concanavalin A (Con A). The effect of interferon becomes evident within 3-6 h and is maximal within 36-48 h. Highly purified human fibroblast interferon (> 2 x 10(8) U/mg of protein sp act; concentration; 640 U/ml) caused approximately 85% inhibition of capping of fluorescein-conjugated Con A in interferon-sensitive HeLa-S3 cells at 36 h from the beginning of treatment.

Full Text

Duke Authors

Cited Authors

  • Pfeffer, LM; Wang, E; Tamm, I

Published Date

  • August 1, 1980

Published In

Volume / Issue

  • 152 / 2

Start / End Page

  • 469 - 474

PubMed ID

  • 6156989

International Standard Serial Number (ISSN)

  • 0022-1007

Language

  • eng

Conference Location

  • United States