Direct electrochemistry of hemoglobin in egg-phosphatidylcholine films and its catalysis to H(2)O(2).

Journal Article (Journal Article)

Direct electrochemistry of hemoglobin was observed in stable thin film composed of a natural lipid (egg-phosphatidylcholine) and hemoglobin on pyrolytic graphite (PG) electrode. Hemoglobin in lipid films shows thin layer electrochemistry behavior. The formal potential E degrees ' of hemoglobin in the lipid film was linearly varied with pH in the range from 3.5 to 7.0 with a slope of -46.4 mV pH(-1). Hemoglobin in the lipid film exhibited elegant catalytic activity for electrochemical reduction of H(2)O(2), based which a unmediated biosensor for H(2)O(2) was developed.

Full Text

Duke Authors

Cited Authors

  • Han, X; Huang, W; Jia, J; Dong, S; Wang, E

Published Date

  • September 2002

Published In

Volume / Issue

  • 17 / 9

Start / End Page

  • 741 - 746

PubMed ID

  • 12191922

International Standard Serial Number (ISSN)

  • 0956-5663

Digital Object Identifier (DOI)

  • 10.1016/s0956-5663(02)00052-0


  • eng

Conference Location

  • England