Tungstoborate and tungstogermanate heteropoly compounds containing rare earth elements with the general formula K15[Ln(BW11O39)2].nH2O and K13[Ln(GeW11O39)2].nH2O, where Ln = La, Ce, Pr, Nd, Sm, have been synthesized and characterized by elemental analysis, IR, 183W NMR spectra. The results of experiments on cytotoxicity and anti-influenza virus activities using cell-cultivation method showed that four compounds among them exhibited good inhibitory effect on influenza virus.