[Quantitative study of the cellular nuclear DNA contents in odontogenic cysts and ameloblastoma].

Journal Article (English Abstract;Journal Article)

OBJECTIVE: To investigate the proliferative potential of the epithelial cells in odontogenic keratocyst, radicular cyst, dentigerous cyst and ameloblastoma. METHODS: DNA contents and ploidy of basal and spinous cells in keratocyst, radicular cyst, dentigerous cyst, and the peripheral column cells and central reticular cells in ameloblastoma were analysis respectively. RESULTS: The more and higher DNA contents and the proliferating ploidy of keratocyst and ameloblastoma than those of radicular cyst and dentigerous cyst indicate the active proliferating potential. The spinous cells showed more active proliferating growth than the basal cells of keratocyst. The higher DNA contents of radicular cyst are related to the stimulus of the inflammation. The dentigerous cysts have more di-ploidy cells without active growth potential. CONCLUSIONS: The active cell proliferating growth in keratocyst and ameloblastoma is probably the pathological basis of their local aggressive biological behavior.

Full Text

Duke Authors

Cited Authors

  • Wang, E; Yu, G; Zhang, Z; Gao, Y

Published Date

  • November 2002

Published In

Volume / Issue

  • 37 / 6

Start / End Page

  • 421 - 424

PubMed ID

  • 12641953

International Standard Serial Number (ISSN)

  • 1002-0098


  • chi

Conference Location

  • China