Infection of artificial air pouches in the connective tissue of mice with Neisseria gonorrhoeae.

Journal Article (Journal Article)

Artificial air pouches in the connective tissue of mice were evaluated as a means of studying Neisseria gonorrhoeae infections. Animals inoculated with type-1 N. gonorrhoeae cells developed an infection characterised by infiltration of polymorphonuclear leucocytes. Viable cocci could be recovered from the air pouches for up to 10 days after infection and intracellular cocci were evident in electronmicrographs within connective-tissue fibroblasts for at least 35 days, indicating that a persistent infection had been established. The mouse air pouch should be of value in the study of gonococcal and other infections.

Full Text

Duke Authors

Cited Authors

  • Clark, JM; Weinhold, KJ

Published Date

  • May 1979

Published In

Volume / Issue

  • 12 / 2

Start / End Page

  • 233 - 237

PubMed ID

  • 110937

International Standard Serial Number (ISSN)

  • 0022-2615

Digital Object Identifier (DOI)

  • 10.1099/00222615-12-2-233


  • eng

Conference Location

  • England