The liver--a potential new player in islet regeneration?

Journal Article (Journal Article)

Pancreatic islet beta cell mass expands in response to certain physiological conditions such as pregnancy and obesity, but the signaling pathways involved are not well understood. Possible insights come from a newly described regulatory circuit through which obesity-enhanced kinase signaling in the liver triggers expansion of islet mass and enhanced insulin secretion.

Full Text

Duke Authors

Cited Authors

  • Moss, LG; Newgard, CB

Published Date

  • January 7, 2009

Published In

Volume / Issue

  • 9 / 1

Start / End Page

  • 5 - 6

PubMed ID

  • 19117540

Pubmed Central ID

  • 19117540

Electronic International Standard Serial Number (EISSN)

  • 1932-7420

Digital Object Identifier (DOI)

  • 10.1016/j.cmet.2008.12.009


  • eng

Conference Location

  • United States